Matériels à disposition
- Spectromètre imageur horizontal 7T Bruker/ diamètre 11 cm, Avance II-BGA 9, accès 9 cm, gradients 300 mT/m.
- Software d’acquisition : Paravision 6.0.1 (Bruker) avec licences pour imagerie standard/SRM/imagerie de diffusion, EPI,
- Antennes constructeur:
- Antennes volumiques émission/réception : 68, 32 et 24 mm
- Antennes de surface activement découplées
- Antennes propres BIOMAPS :
- Berceaux de contention adaptés à chaque type d’antenne
- Software de traitement : Paravision 6.0.1 (Bruker)/ AMIRA (ThermoFischer)
Local équipé et pièce de préparation
Contact et accès
Demande d’accès :
Renvoyer ce document par e-mail aux responsables du plateau Micro-IRM 7T.
Demande_de_projet_PF_IRM_7T et 1.5T
Suivant les thématiques de votre projet et vos besoins, une première rencontre sera organisée entre votre équipe, les chercheurs de BIOMAPS susceptibles de vous aider.
Contacts:
| Responsable scientifique Catherine Sébrié | Responsable technique Laurène Jourdain |
Publications liées au plateau
Multimodal imaging for tumour characterization from micro- to macroscopic level using a newly developed dorsal chamber designed for long-term follow-up. Rouffiac V, Roux KS, Salomé-Desnoulez S, Leguerney I, Ginefri JC, Sébrié C, Jourdain L, Lécluse Y, Laplace-Builhé C. J Biophotonics. 2020 Jan;13(1):e201900217. doi: 10.1002/jbio.201900217. Epub 2019 Oct 23.
A multiscale analysis in CD38-/- mice unveils major prefrontal cortex dysfunctions. Martucci LL, Amar M, Chaussenot R, Benet G, Bauer O, de Zélicourt A, Nosjean A, Launay JM, Callebert J, Sebrié C, Galione A, Edeline JM, de la Porte S, Fossier P, Granon S, Vaillend C, Cancela JM. FASEB J. 2019 May;33(5):5823-5835. doi: 10.1096/fj.201800489R. Epub 2019 Mar 7.
Proton minibeam radiation therapy widens the therapeutic index for high-grade gliomas. Prezado Y, Jouvion G, Patriarca A, Nauraye C, Guardiola C, Juchaux M, Lamirault C, Labiod D, Jourdain L, Sebrie C, Dendale R, Gonzalez W, Pouzoulet F. Sci Rep. 2018 Nov 7;8(1):16479. doi: 10.1038/s41598-018-34796-8.
Transfer of Minibeam Radiation Therapy into a cost-effective equipment for radiobiological studies: a proof of concept. Prezado Y, Dos Santos M, Gonzalez W, Jouvion G, Guardiola C, Heinrich S, Labiod D, Juchaux M, Jourdain L, Sebrie C, Pouzoulet F. Sci Rep. 2017 Dec 11;7(1):17295. doi: 10.1038/s41598-017-17543-3.
Proton minibeam radiation therapy spares normal rat brain: Long-Term Clinical, Radiological and Histopathological Analysis. Prezado Y, Jouvion G, Hardy D, Patriarca A, Nauraye C, Bergs J, González W, Guardiola C, Juchaux M, Labiod D, Dendale R, Jourdain L, Sebrie C, Pouzoulet F. Sci Rep. 2017 Oct 31;7(1):14403. doi: 10.1038/s41598-017-14786-y.
Diabetic microangiopathy: impact of impaired cerebral vasoreactivity and delayed angiogenesis after permanent middle cerebral artery occlusion on stroke damage and cerebral repair in mice. Poittevin M, Bonnin P, Pimpie C, Rivière L, Sebrié C, Dohan A, Pocard M, Charriaut-Marlangue C, Kubis N. Diabetes. 2015 Mar;64(3):999-1010. doi: 10.2337/db14-0759. Epub 2014 Oct 6.
Arginine butyrate per os protects mdx mice against cardiomyopathy, kyphosis and changes in axonal excitability. Vianello S, Bouyon S, Benoit E, Sebrié C, Boerio D, Herbin M, Roulot M, Fromes Y, de la Porte S. Neurobiol Dis. 2014 Nov;71:325-33. doi: 10.1016/j.nbd.2014.08.023. Epub 2014 Aug 26.
Spatial and temporal MRI profile of ischemic tissue after the acute stages of a permanent mouse model of stroke. Bogaert-Buchmann A, Poittevin M, Po C, Dupont D, Sebrié C, Tomita Y, Trandinh A, Seylaz J, Pinard E, Méric P, Kubis N, Gillet B. Open Neuroimag J. 2013;7:4-14. doi: 10.2174/1874440001307010004. Epub 2013 Feb 1.
Arginine butyrate: a therapeutic candidate for Duchenne muscular dystrophy. Vianello S, Yu H, Voisin V, Haddad H, He X, Foutz AS, Sebrié C, Gillet B, Roulot M, Fougerousse F, Perronnet C, Vaillend C, Matecki S, Escolar D, Bossi L, Israël M, de la Porte S. FASEB J. 2013 Jun;27(6):2256-69. doi: 10.1096/fj.12-215723. Epub 2013 Feb 21.
DYRK1A: a master regulatory protein controlling brain growth. Guedj F, Pereira PL, Najas S, Barallobre MJ, Chabert C, Souchet B, Sebrie C, Verney C, Herault Y, Arbones M, Delabar JM. Neurobiol Dis. 2012 Apr;46(1):190-203. doi: 10.1016/j.nbd.2012.01.007. Epub 2012 Jan 26. Erratum in: Neurobiol Dis. 2012 Aug;47(2):294.
Porous metal-organic-framework nanoscale carriers as a potential platform for drug delivery and imaging. Horcajada P, Chalati T, Serre C, Gillet B, Sebrie C, Baati T, Eubank JF, Heurtaux D, Clayette P, Kreuz C, Chang JS, Hwang YK, Marsaud V, Bories PN, Cynober L, Gil S, Férey G, Couvreur P, Gref R. Nat Mater. 2010 Feb;9(2):172-8. doi: 10.1038/nmat2608. Epub 2009 Dec 13.
First evaluation of temporal and spatial fractionation in proton minibeam radiation therapy of glioma-bearing rats. Bertho A and Ortiz R, Juchaux M, Gilbert C, Lamirault C, Pouzoulet F, Polledo L , Liens A , Warfving N , Sebrie C, Jourdain L, Patriarca A, de Marzi L and Prezado Y CAncers 2021, 13, 4865. doi.org/10.3390/cancers13194865
Emotional behavior and brain anatomy of the mdx52 mouse model of Duchenne muscular dystrophy Saoudi A, Zarrouki F, Sebrie C, Izabelle C, Goyenvalle A, and Vaillend C Dis Model Mech. 2021 Sep 1;14(9):dmm049028. doi: 10.1242/dmm.049028. Epub 2021 Sep 21. PMID: 34546327
X-rays minibeam radiation therapy at a conventional irradiator: Pilot evaluation in F98-glioma bearing rats and dose calculations in a human phantom. Sotiropoulos M, Brisebard E, Le Dudal M, Jouvion G, Juchaux M, Crépin D, Sebrie C, Jourdain L, Labiod D, Lamirault C, Pouzoulet F, Prezado Y. Clin Transl Radiat Oncol. 2021 Jan 8;27:44-49. doi: 10.1016/j.ctro.2021.01.001. eCollection 2021 Mar.PMID: 33511291
Spatially Modulated Proton Minibeams Results in the Same Increase of Lifespan as a Uniform Target Dose Coverage in F98-Glioma-Bearing Rats. Lamirault C, Brisebard E, Patriarca A, Juchaux M, Crepin D, Labiod D, Pouzoulet F, Sebrie C, Jourdain L, Le Dudal M, Hardy D, De Marzi L, Dendale R, Jouvion G, Prezado Y. Radiat Res. 2020 Dec 1;194(6):715-723. doi: 10.1667/RADE-19-00013.1.PMID: 32991712
Ultrasound Molecular Imaging of Renal Cell Carcinoma: VEGFR targeted therapy monitored with VEGFR1 and FSHR targeted microbubbles. Ingels A, Leguerney I, Cournède PH, Irani J, Ferlicot S, Sébrié C, Benatsou B, Jourdain L, Pitre-Champagnat S, Patard JJ, Lassau N. Sci Rep. 2020 Apr 30;10(1):7308. doi: 10.1038/s41598-020-64433-2. PMID: 32355171