Jean-Luc Gennisson _ En

CNRS Research Director (Professor)

Head of Methodological Developments and Instrumentation Team

Ph.D in acoustics

specialized in Electronics and Instrumentation

contact

  • Transient elastography 1D, 2D & 3D and supersonic shear imaging
  • Anisotropy in elastography
  • Shear waves nonlinearity and acoustoelasticity
  • Shear viscosity and shear wave dispersion
  • MRI Passive elastography
  • Ultrafast ultrasound imaging

Duties

  • Council member of BioMaps laboratory (2020 – …)
  • Council member of  Graduate School « Sciences de l’Ingénierie et des Systèmes » from Paris-Saclay University (2021-2025)
  • Reviewer for IEEE UFFC, Ultrasound in Medicine and Biology, Journal of Acoustical Society of America, Physics Medicine and Biology, Journal of Biomechanics, Applied Physics Letters.
  • Associate editor for Scientific Reports, Frontiers in Physics
  • Organizer of 7 International Workshops
  • Co-organizer of IUS-IEEE 2016 (International Ultrasonic symposium)
  • Co-founder of the « Neuroflows » company in 2016 that became « Iconeus » in 2018.

Current supervisions and associated fundings

          Ph. D.:

  • Maxime LERICHE – ANR FATUS Project (JLG PI)  Muscular fat quantification by ultrasound imaging 
  • Axel NIERDING – ANR ULTRADIAPH (Preventing diaphragm dysfunction in the intensive care unit with innovative ultrasound biomarkers)

         Post-doctoral fellows:

  • Lim-Anna SIEU – High resolution and sensitive PET/US combination for neuroimaging 

Alumni

          Ph. D.:

  • Thomas Poulard -RESPIMYO project (Multiparametric ultrasound imaging of diaphragm)  
  • Marion BIED – Intramuscular fat quantification by ultarfast ultarsound
  • Ha-Hien Phuong NGO – ANR INNOVAN Project (JLG PI) (INNOvations in elastography to quantify Viscosity and ANisotropy of muscle)  
  • Célestine ANGLA – Rapid transcranial acoustic simulations and adaptive imaging for personalized dosimetry in ultrasound brain therapy

         Post-doctoral fellows:

  • Gwenaël PAGE – BPALP Project (JLG PI) – INCA Plan Cancer (Brain palpation by using passive MR elastography)
  • Corentin CORNU– ANR ULTRADIAPH (Preventing diaphragm dysfunction in the intensive care unit with innovative ultrasound biomarkers)
  • Lenin CHINCHILLAPERFUSION Project (JLG PI) – Bettencourt-Schueller Foundation – (Kidney PERFusion mapping by ultrafast UltraSound Imaging)
  • Steve BEUVE – FULGUR Project – ANR France 2030 – (Towards and individualized periodization of training load adapted to muscle properties to reduce injury occurence in sprint running)
  • Khalil RACHID – BPALP Project (JLG PI) – INCA Plan Cancer (Brain palpation by using passive MR elastography)
  • Djallel BELHADJ – DIAMAND Project – PTC CEA – (Minimalist and robust measurement of arterial diameter for a portable medical device)

Industrial collaborations

Teaching

  • Ultrasonore Imaging, Doppler, Elastography,
    • Master 2 Level – Medical Physics at University Paris-Saclay, l’ENSTA, University Paris-Descartes

Trainings

  • Authorization to conduct preclinical protocols.
  • Laser clearance

Prizes and rewards

Post-doctoral fellow

The Laboratory of Biorheology and Medical Ultrasonics, Montréal university, Canada

—-

– Sol-gel transition in agar-gelatin mixture
– Study of blood coagulation with transient elastography
 – PVA Characterization

Adress : Laboratoire de biorhéologie et d’ultrasonographie médicale,
900, St-Denis, suite R11.720
Montréal, Québec
Canada, H2X 0A9.

—-

Thesis

Ph.D. – Thèse de doctorat 

Ph.D. – Habilitation à diriger des recherches

Talks & Publications

Filmed plenary session at « 33ième congrès international de biomécanique des sports sur l’élastographie du muscle (Juillet 2015) »

Publications (isi web of knowledge)

Publications (google scholar)

Publications ORCID

136 Articles in international peer-reviewed journals
49 Proceedings
13 Invited talks
16 Patents
1 Book : « Ultrasound Elastography for Biomedical Applications and Medicine« 

 

Relevant publications

  1. “4D Ultrafast shear wave imaging.” J.L. Gennisson, J. Provost, T. Deffieux, C. Papadacci, M. Imbault, M. Pernot, M. Tanter. IEEE Trans. Ultrason., Ferroelec., Freq. Contr., 62(6), pp. 1059−1065, 2015. Prize of the 2015 Outstanding paper award in Trans. Ultrason., Ferroelec., Freq. ContrDOI: 10.1109/TUFFC.2014.006936
  2. “3D ultrafast ultrasound imaging in vivo.” J. Provost, C. Papadacci, J.-E. Arango, M. Imbault, M. Fink, J.L. Gennisson, M. Tanter M. Pernot. Phys. Med. & Bio., 59 (19), L1-L13, 2014. 2015 Robert’s prize for the best paper in Physics Medicine and Biology. 2019 Rotblat’s medal for the highest cited paper in five years.  DOI: 10.1088/0031-9155/59/19/L1
  3. “Viscoelastic and anisotropic mechanical properties of in vivo muscle tissue assessed by supersonic shear imaging”, J.L. Gennisson, T. Deffieux, E. Macé, G. Montaldo, M. Fink, M. Tanter, Ultr. Med. & Bio. 36 (5), 789-801, 2010. (813 citations, google scholar Sep. 2022).  DOI: 10.1016/j.ultrasmedbio.2010.02.013
  4. “Ultrasound elastography: principles and techniques”, J.L. Gennisson, T. Deffieux, M. Fink, M. Tanter, Diag. Interv. Im., 94 (5), pp. 487-495, 2013. (515 citations, google scholar Aug. 2020).  DOI: 10.1016/j.diii.2013.01.022
  5. “Quantitative assessment of breast lesions viscoelasticity using supersonic shear imaging technique: Initial clinical investigation.” M. Tanter, J. Bercoff, A. Athanasiou, T. Deffieux, J.L. Gennisson, G. Montaldo, A. Tardivon, M. Fink. Ultr. Med. & Bio., 34 (9), pp. 1373-1386, 2008. (865 citations, google scholar Sep. 2022).  DOI: 10.1016/j.ultrasmedbio.2008.02.002
  6. “A diffraction correction for storage and loss moduli imaging using radiation force based elastography.” E. Budelli, J. Brum, M. Bernal, T. Deffieux, M. Tanter, P. Lema, C. Negreira, J.L. GennissonPhys. Med. Bio., vol. 62 (1), pp. 91-106, 2017. (I.F. 2.883). DOI: 10.1088/1361-6560/62/1/91
  7. “In vivo quantification of the shear modulus of the human Achilles tendon during passive loading using shear wave dispersion analysis.” C. Helfenstein-Didier, R.J. Andrade, J. Brum, F. Hug, M. Tanter, A. Nordez, J.L. GennissonPhys. Med. Bio., 61 (6), pp. 2485−2496, 2016. (I.F. 2.883). DOI: 10.1088/0031-9155/61/6/2485
  8. “Tumor Stiffening, a Key Determinant of Tumor Progression, is Reversed by Nanomaterial-Induced Photothermal Therapy”, I. Marangon, A.A. K. Silva, T. Guilbert, J. Kolosnjaj-Tabi, C. Marchiol, S. Natkhunarajah, F. Chamming’s, C. Ménard, A. Bianco, J.L. Gennisson, G. Renault, F. Gazeau, Theranostics, vol. 7 (2), pp. 329-343, 2017. (I.F. 8.712). DOI: 10.7150/thno.17574
  9. “Mechanical induction of the tumorogenic β-catenin pathway by tumour growth pressure” M.E. Fernández-Sánchez, S. Barbier, J. Whitehead, G. Béalle, A. Michel, H. Latorre-Ossa, C. Rey, L. Fouassier, A. Claperon, L. Brullé, E. Girard, N. Servant, T. Rio-Frio, H. Marie, S. Lesieur, C. Housset, J.L. Gennisson, M. Tanter, C. Ménager, S. Fre, S. Robine, E. Farge. Nature, 523, pp. 92−95, 2015. (I.F. 42.778). DOI: 10.1038/nature14329
  10. “EEG and functional ultrasound imaging in mobile rats.” L.A. Sieu, A. Bergel, E. Tiran, T. Deffieux, M. Pernot, J.L. Gennisson, M. Tanter, I. Cohen. Nature Methods, 12 (9), pp. 831−834, 2015. (I.F. 30.822).  DOI: 10.1038/nmeth.3506